Overordnede kursusmål
--Human near-field consumer exposure and far-field population
exposure/toxicity & ecotoxicity modeling with the global
scientific consensus model USEtox 3.0--
There is an increasing need for methods to assess impacts of toxic
chemical emissions on human health and ecosystems including
consumer exposure. This course provides a practical overview of
multimedia chemical fate modelling, near-field and far-field
multi-pathway human exposure modelling, ecosystem and human health
effects dose-response modelling, and comparative indicators for
human-toxicological and ecotoxicological impacts. We explain basic
concepts of environmental mass balance modelling including
partitioning, first order cross-media transport, and persistence.
We further introduce the concept of assessing multiple transfers
between near-field and far-field environments and resulting
exposures for consumers and the general population, discussing data
and models available for detergents, building materials, food
contact materials and personal care products. Along a series of
practical examples, we will illustrate how fate, exposure, effect
and damage factors can be combined to construct factors to
characterize chemical emissions and chemicals in consumer products,
building on the USEtox scientific consensus model and
USEtox-compatible near-field models. We will conclude with a
demonstration of how the models can be used in various
applications, including the prioritization and ranking of chemicals
for institutions like the European Commission or the U.S.
Environmental Protection Agency.
Teachers will be Peter Fantke (USEtox Managing Director) and
members of the USEtox team.
Læringsmål
En studerende, der fuldt ud har opfyldt kursets mål, vil kunne:
- Explain and apply exposure science methods used in life-cycle
impact assessment, chemical substitution, and comparative risk
assessment
- Use and evaluate basic tools for mass-balance, fate modeling,
intake fraction, and effect factor estimation
- Review underlying model assumptions and uncertainties
- Evaluate data needs along with data and knowledge gaps in
toxicity characterization
- Explain the scientific fundamentals of chemical impact
assessment for a broad range of environmental emissions
- Perform your own assessment using the USEtox scientific
consensus model and related near-field exposure models and
interpret results
- Find data sources, implement new substances into USEtox, and
modify existing modules
- Discuss applicability and limitations of USEtox model, data and
results in different application fields including life cycle
assessment, product environmental footprinting and comparative risk
assessment
Kursusindhold
Participants/students will have hands-on access to all model, data,
documentation and reading files during the course and will be able
to take all files back home. New substances will be characterized
and participants/students may bring their own list of substances of
interest for the exercises.
The course is structured as follows:
- Week 1: preparatory reading (reading material will be sent 1
months in advance)
- Week 2: interactive on-site lectures and hands-on exercises
(physical presence required)
- Week 3: preparation of report around own exercise project
Litteraturhenvisninger
Rosenbaum et al. 2008
http://doi.org/10.1007/s11367-008-0038-4
Fantke et al. 2021
http://doi.org/10.1007/s11367-021-01889-yBemærkninger
2500 EUR for professionals, 300 EUR for students (proof required)
Sidst opdateret
25. april, 2023